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KMID : 0366919960080010045
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Sungkyun Pharmceutical Journal
1996 Volume.8 No. 1 p.45 ~ p.50
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High Incidence of Multidrug-Resistant Streptococcus pneumoniae in South Korea
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KIM, SU-NAM
KIM, SEUNG-WHAN/CHOI, IN-HWA/PYO, SUHK-NEUNG/RHEE, DONG-KWON
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Abstract
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Streptococcus pneumoniae was isolated from patients with bacteremia, meningitis, pneumonia, and otitis media and used to determine susceptibility to various antibiotics. Of 105 isolates, 51% to 83% were resistant to 6 antibiotics (i.e., the percentages of resistance to penicillin, ampicillin, cephalothin, chloramphenicol, tetracycline, and erythromycin were 78%, 67%, 51%, 56%, 83% and 58% respectively). Also 66 of the 105 isolates were multidrug resistant. Seventy-eight percent of multidrug-resistant strains were highly resistant to tetracycline (minimum inhibitory concentration [MIC] ≥50㎍/ml), and 39% of multidrug-resistant strains were also highly resistant to erythromycin (MIC≥128㎍/ml) However, only 4% of the 105 isolates were resistant to cefotaxime.
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KEYWORD
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